Ro4938581 is a nootropic drug invented in 2009 by a group Performing for Hoffmann-La Roche, which acts as a subtype-selective inverse agonist within the αfive subtype in the benzodiazepine binding web-site about the GABAA receptor. It has very good selectivity for your α5 subtype and did not produce convulsant or anxiogenic outcomes in animal res